This patient is treated for pulmonary arterial hypertension with ambrisentan. The ambrisentan-tablets are taken orally at a dose of 5 mg once daily.

Warning

Ambrisentan should not be used in combination with bosentan, NO, dopamine,

dobutamin, vardenafil, tadenafil or with experimental drugs.

Volibris®

Pink square with 5mg or 10 mg ambrisentan. Ambrisentan is a selective endothelin

receptor antagonist binding to receptor A. It has been proven to reduce the pulmonary

vascular resistance, resulting in a greater cardic output at the same heart rate.

Treatment guidelines

Patients may develop abnormal liver function. Regular checking of liver function is

necessary. In case of AST or ALT greater than 3 ULN, stop treatment. Often several

medications for pulmonary hypertension are prescribed concomitantly. In case of

problems,refer to the product description of all medications to see if they result

from medication interaction, side effects or medication effects. Immediately contact

the patient's pulmonologist in case of problems