-------- Never stop infusion, life-threatening! ---------
This patient is treated for pulmonary hypertension with epoprostenol. It is
continously, intravenously administered via an implanted infusion system (Port-aCath®) or central venous line.
Epoprostenol
Epoprostenol is a potent vasodilotor, affecting both the pulmonary and systemic
circulation. It also inhibits platelet aggregation.
Treatment guidelines
Stopping the infusion is life threatening! In case of problems with the Port-a-Cath® or
central venous line, an IV in the arm must be started immediately. The pump tubing will
screw directly onto the IV in the arm. To prevent vascular damage, restore the Port-aCath®/central venous line or start an infusion of dexamethason (solved in NaCl 0.9%) 2 mg
per 24h in the same line.
Make sure the pump is running. The patient always carries a back up pump, medication
and spare supplies. Patient/partner knows what to do in case of problems. Often several
medications for pulmonary hypertension are prescribed concomitantly. In case of
problems, refer to the product description of all medications to see if they result from
medication interaction, side effects or medication effects. Immediately contact the
patient’s pulmonologist in case of problems.
Problems that may arise
- The needle is pulled out of the Port-a-Cath® or obstruction central venous line: Make sure the medication is continued by an IV in the arm. Then insert a new needle in the Port-a-Cath® for continuation of the medication.
- Infection: The patient has fever or chills. There is foul odor, tenderness, pus, redness, warmth or swelling at the insertion site of the central venous system. Administer antibiotics and replace the Port-a-Cath® or central venous line if necessary.